Identification of novel surface-exposed proteins of Rickettsia rickettsii by affinity purification and proteomics.
Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, is the most pathogenic member among Rickettsia spp.Surface-exposed proteins (SEPs) of R.rickettsii may play important roles in Power Adapter its pathogenesis or immunity.In this study, R.rickettsii organisms were surface-labeled with sulfo-NHS-SS-biotin and the labeled prot